Is spinal dexmedetomidine aggravating hypotension after tourniquet deflation?

Low-dose Bupivacaine with Dexmedetomidine Prevents Hypotension After Spinal Anesthesia

Background: We assessed whether intrathecal low-dose bupivacaine with dexmedetomidine could reduce the incidence of spinal anesthesia (SA)-related hypotension. Methods: In total, 47 patients undergoing urological or orthopedic surgery under SA were randomized into two groups. SA was induced using 12.5 mg of hyperbaric bupivacaine alone (Group B; n = 24 patients) or 6 mg of hyperbaric bupivacain...

Influence of systemic hypotension on skeletal muscle ischemia-reperfusion injury after 4-hour tourniquet application.

OBJECTIVE Tourniquet use for extremity hemorrhage control is common in military trauma. Tourniquet use may be accompanied by systemic hypotension, but this phenomenon has not been studied. We aimed to define the muscle effects of the combined insult of tourniquet-induced skeletal muscle ischemia-reperfusion injury (I-R) and hemorrhagic hypotension. DESIGN After a 33% carotid arterial hemorrha...

Heart rate variability predicts severe hypotension after spinal anesthesia.

BACKGROUND Hypotension due to vasodilatation after spinal anesthesia (SA) may be harmful. Heart rate variability, an indirect measure of autonomic control, may predict hypotension. METHODS One hundred patients were studied. Retrospectively, heart rate variability was analyzed in 30 patients, classified depending on the lowest systolic blood pressure (SBP) after SA. Seventy patients were studi...

Relation between preoperative autonomic function and blood pressure change after tourniquet deflation during total knee replacement arthroplasty

BACKGROUND Tourniquets are used to provide a bloodless surgical field for extremities. Hypotension due to vasodilation and bleeding after tourniquet deflation is a common event. Hemodynamic stability is modulated by the autonomic nervous system (ANS). Heart rate variability (HRV) is a sensitive method for detecting individuals who may be at risk of hemodynamic instability during general anesthe...

Spinal Manifestations of Intracranial Hypotension